BPC-157 10mg
Identity
- CAS number
- 137525-51-0
- Molecular formula
- C62H98N16O22
- Molecular weight
- 1419.53
Physical form
- Appearance
- White lyophilised powder
- Purity
- 99%+ (HPLC)
- Solubility
- Soluble in bacteriostatic water
Handling
- Storage
- -20C, protected from light
- Shelf life
- 24 months from date of manufacture, sealed
Also known as Body Protection Compound 157, PL 14736, Pentadecapeptide BPC 157
£34.00
Synthetic pentadecapeptide, 10mg lyophilised. Studied in tissue repair and angiogenesis models. Certificate of analysis per batch.
25 in stock
- Dispatch Same day if you order before the cut off, tracked
- Documentation Your batch certificate is emailed when it ships
- Storage -20C, protected from light
Worth knowing: almost all published BPC-157 research is in animal models rather than people, so treat the findings as early stage. That is normal for a research compound and it is why we sell it as one.
Product description
A synthetic pentadecapeptide of fifteen amino acids, derived from a partial sequence identified in human gastric juice. Supplied lyophilised in a 10mg vial.
Research context
BPC-157 is among the most frequently requested compounds in laboratory work on tissue repair. Published research using it concentrates on angiogenic signalling, fibroblast migration and the behaviour of tendon and ligament cells in culture. It is stable across a wide pH range in vitro, which is one reason it appears so often in gastrointestinal models specifically. Almost all published work is in vitro or in animal models.
Handling notes
Reconstitute with bacteriostatic water added slowly down the wall of the vial rather than directly onto the cake. Swirl to dissolve, do not shake. Store the sealed vial frozen and protected from light. Once in solution, aliquot before freezing rather than repeatedly thawing the whole volume, because BPC-157 tolerates a couple of freeze thaw cycles and not five or six.
Worth knowing
It is commonly studied alongside TB-500, which is why we also supply the two as a single blended vial. If your protocol calls for both, the blend removes a reconstitution step and one opportunity for error.
Documentation
This batch ships with its own certificate of analysis showing HPLC purity and mass spectrometry identity confirmation. The batch reference is recorded against your order, so a result generated months from now can be traced back to this specific lot.
Intended use
Supplied strictly for laboratory research use. Not a medicine. Not for human or veterinary consumption, and not for any diagnostic or therapeutic use.
Research background
The short version
Our best selling peptide, and the one most people in repair research start with. It is a fifteen amino acid sequence first identified in stomach fluid, and most of the research looks at how it affects new blood vessel growth. Worth knowing that nearly all of that work is in animal models.
BPC-157 is a synthetic pentadecapeptide derived from a partial sequence identified in human gastric juice. The research literature is substantial in volume but concentrated almost entirely in animal models, and that concentration is the single most important thing to understand about it.
Where it came from
Derived from body protection compound, a protein fragment identified in gastric juice. The synthetic fifteen amino acid sequence is what is supplied and studied. Published work runs from the 1990s onward, largely from a small number of research groups.
How it is thought to work
No single receptor has been identified. Proposed mechanisms centre on effects on angiogenic signalling, particularly involving vascular endothelial growth factor pathways, and on interaction with nitric oxide systems.
The absence of a defined receptor is worth stating plainly. It means the mechanistic picture is inferred from downstream observations rather than established from binding studies, and it is a live limitation in the literature rather than a settled question.
What it is studied for
What the published research found, and what it was tested in. We list the model against each one so you can judge how far the findings go.
- Angiogenesis Effects on new vessel formation, which is the mechanism most frequently proposed to underlie observations in repair models. What they found Upregulation of VEGF expression and VEGFR2 signalling in injured rat tissue, with one study reporting a roughly threefold to fourfold increase in VEGFR2 expression against controls. Increased vessel density followed the receptor change rather than preceding it. Tested in Cell culture, rodent models
- Tendon and ligament cell behaviour Fibroblast migration and survival in culture, and healing rates in animal injury models. What they found Accelerated Achilles tendon healing in rats, with treated animals showing improved biomechanical strength against controls. Microarray work on rat tendon fibroblasts found growth hormone receptor among the most upregulated genes. Tested in Tendon fibroblast culture, rodent models
- Gastrointestinal models The original context for the compound, and where the largest body of animal work sits. Stability across a wide pH range is the property that makes it usable in these models. What they found Improved healing across a range of induced rat gastrointestinal lesions, including fistula models where untreated controls failed to heal. This is the largest body of work on the compound and it is almost entirely rodent. Tested in Rodent models
Further reading
- Brain-gut axis and pentadecapeptide BPC 157: theoretical and practical implications Read the paper
- Stable gastric pentadecapeptide BPC 157 in honeybee and mammal therapy Read the paper
Specification
| CAS number | 137525-51-0 |
|---|---|
| Molecular formula | C62H98N16O22 |
| Molecular weight | 1419.53 |
| Purity | 99%+ (HPLC) |
| Appearance | White lyophilised powder |
| Solubility | Soluble in bacteriostatic water |
| Storage | -20C, protected from light |
| Shelf life | 24 months from date of manufacture, sealed |
What you get
- The vial BPC-157 10mg. Sealed and labelled with the compound and its batch reference.
- Certificate of analysis For your batch specifically. Emailed when your order ships and available on this page now.
- Cold chain packaging Gel pack and insulation. We ship these early in the week so nothing sits in a depot over the weekend.
- Plain outer packaging Plain on the outside for your privacy. Everything inside is clearly labelled.
How it compares
How this compares to the compounds people usually weigh it against. Only the specs that actually differ are shown.
| Specification | This product BPC-157 10mg | TB-500 10mg | BPC-157 and TB-500 Blend 10mg |
|---|---|---|---|
| Molecular weight | 1419.53 | 4963.44 | |
| Price | £34.00 | £32.00 | £48.00 |
Questions about this compound
How should BPC-157 10mg be stored?
Store the sealed vial at -20C, protected from light. Sealed and held at that condition it carries a shelf life of 24 months from date of manufacture, sealed from the date of manufacture. Once reconstituted, shelf life shortens considerably and the solution should be aliquoted before freezing rather than thawed repeatedly.
How is BPC-157 10mg reconstituted?
Soluble in bacteriostatic water. Add the solvent slowly down the inside wall of the vial rather than directly onto the material, then swirl gently to dissolve. Do not shake, vortex or sonicate to speed it up. A cloudy solution that will not clear usually means the wrong solvent rather than a poor batch.
What purity is this batch and how is it verified?
This item is supplied at 99%+ (HPLC), measured by high performance liquid chromatography. Identity is confirmed separately by mass spectrometry. Both results appear on the certificate of analysis for the batch you receive, not for a previous lot.
Can I see the certificate of analysis before ordering?
Yes. It is linked in the documentation section of this page. If no certificate is shown against this listing, ask before ordering rather than after.
Is BPC-157 10mg the same as the other names it appears under?
Yes. BPC-157 10mg also appears in the literature as Body Protection Compound 157, PL 14736, Pentadecapeptide BPC 157. They refer to the same compound, which is worth knowing when searching for prior work because results are split across the names.
Can this be used in humans or animals?
No. This is supplied strictly as a laboratory reagent for in vitro research. It is not a medicine, it is not licensed for human or veterinary use, and it should not be administered to a person or an animal. We do not provide dosing or administration guidance.
Handy guides
- Reconstitution and solvents Choosing a solvent, adding it without damaging the peptide, working out concentrations, and the handling errors that cost people a vial.
- Storage and handling Temperature, light, reconstitution and shelf life, and what actually degrades a compound in practice.
- Freeze thaw cycles and shelf life What degrades a peptide in practice, how much a freeze thaw cycle actually costs you, and how to plan aliquots so it stops mattering.
- How to read a certificate of analysis A section by section walkthrough of a peptide certificate: what each figure means, what it does not mean, and the checks worth making before you accept a batch.
