Ipamorelin 10mg
Identity
- CAS number
- 170851-70-4
- Molecular formula
- C38H49N9O5
- Molecular weight
- 711.85
Physical form
- Appearance
- White lyophilised powder
- Purity
- 99%+ (HPLC)
- Solubility
- Soluble in bacteriostatic water
Handling
- Storage
- -20C, protected from light
- Shelf life
- 24 months from date of manufacture, sealed
Also known as Ipamorelin acetate, NNC 26-0161
£30.00
Selective ghrelin receptor pentapeptide, 10mg lyophilised. Used where receptor selectivity is the point of the study.
25 in stock
- Dispatch Same day if you order before the cut off, tracked
- Documentation Your batch certificate is emailed when it ships
- Storage -20C, protected from light
Worth knowing: US regulators declined to add ipamorelin to the compounding bulks list in 2024. That is a US decision rather than a UK one, but useful context if you are following the regulatory picture.
Product description
A synthetic pentapeptide and selective ghrelin receptor ligand. Supplied lyophilised in a 10mg vial.
Research context
Ipamorelin is used in laboratory work where receptor selectivity is the point of the study rather than an incidental property. Its selectivity profile at the ghrelin receptor is the reason it appears in comparative binding work alongside less selective secretagogues. Also referenced as NNC 26-0161.
Handling notes
Reconstitute with bacteriostatic water. At five residues it dissolves quickly and cleanly. Store the sealed vial frozen and protected from light, and aliquot after reconstitution.
Worth knowing
Frequently compared against tesamorelin in the literature, though the two act through different mechanisms, which is a distinction worth making explicit in a methods section.
Documentation
This batch ships with its own certificate of analysis showing HPLC purity and mass spectrometry identity confirmation. The batch reference is recorded against your order, so a result generated months from now can be traced back to this specific lot.
Intended use
Supplied strictly for laboratory research use. Not a medicine. Not for human or veterinary consumption, and not for any diagnostic or therapeutic use.
Research background
The short version
A five amino acid peptide that binds the ghrelin receptor. Its research interest is selectivity: it hits that one receptor and largely leaves related ones alone, which makes it useful as a comparison tool.
Ipamorelin is a synthetic pentapeptide and selective ghrelin receptor ligand. Selectivity rather than potency is the point of it, which is why it appears repeatedly in comparative receptor work.
Where it came from
Developed at Novo Nordisk under the code NNC 26-0161 as part of a programme on growth hormone secretagogues.
How it is thought to work
Binds the growth hormone secretagogue receptor, the ghrelin receptor. Its selectivity profile relative to earlier secretagogues is the property most often studied.
Because earlier compounds in this class had activity at multiple receptors, a selective ligand is useful for isolating which effects belong to which receptor.
What it is studied for
What the published research found, and what it was tested in. We list the model against each one so you can judge how far the findings go.
- Receptor selectivity Binding profile at the ghrelin receptor against related receptors. What they found Selective binding at the growth hormone secretagogue receptor with minimal activity at related receptors, which is the property that distinguishes it from earlier compounds in the class. Tested in Receptor binding assays
- Signalling pathways Second messenger responses following receptor activation. What they found Receptor activation produces the expected second messenger response in cell culture. Tested in Cell culture
- Comparative secretagogue work Set against less selective compounds in the same class. What they found Used as a selective tool compound to separate ghrelin receptor mediated effects from those of less selective secretagogues. Tested in Cell culture, rodent models
Specification
| CAS number | 170851-70-4 |
|---|---|
| Molecular formula | C38H49N9O5 |
| Molecular weight | 711.85 |
| Purity | 99%+ (HPLC) |
| Appearance | White lyophilised powder |
| Solubility | Soluble in bacteriostatic water |
| Storage | -20C, protected from light |
| Shelf life | 24 months from date of manufacture, sealed |
What you get
- The vial Ipamorelin 10mg. Sealed and labelled with the compound and its batch reference.
- Certificate of analysis For your batch specifically. Emailed when your order ships and available on this page now.
- Cold chain packaging Gel pack and insulation. We ship these early in the week so nothing sits in a depot over the weekend.
- Plain outer packaging Plain on the outside for your privacy. Everything inside is clearly labelled.
How it compares
How this compares to the compounds people usually weigh it against. Only the specs that actually differ are shown.
| Specification | This product Ipamorelin 10mg | Tesamorelin 10mg |
|---|---|---|
| Molecular weight | 711.85 | 5135.72 |
| Price | £30.00 | £62.00 |
Questions about this compound
How should Ipamorelin 10mg be stored?
Store the sealed vial at -20C, protected from light. Sealed and held at that condition it carries a shelf life of 24 months from date of manufacture, sealed from the date of manufacture. Once reconstituted, shelf life shortens considerably and the solution should be aliquoted before freezing rather than thawed repeatedly.
How is Ipamorelin 10mg reconstituted?
Soluble in bacteriostatic water. Add the solvent slowly down the inside wall of the vial rather than directly onto the material, then swirl gently to dissolve. Do not shake, vortex or sonicate to speed it up. A cloudy solution that will not clear usually means the wrong solvent rather than a poor batch.
What purity is this batch and how is it verified?
This item is supplied at 99%+ (HPLC), measured by high performance liquid chromatography. Identity is confirmed separately by mass spectrometry. Both results appear on the certificate of analysis for the batch you receive, not for a previous lot.
Can I see the certificate of analysis before ordering?
Yes. It is linked in the documentation section of this page. If no certificate is shown against this listing, ask before ordering rather than after.
Is Ipamorelin 10mg the same as the other names it appears under?
Yes. Ipamorelin 10mg also appears in the literature as Ipamorelin acetate, NNC 26-0161. They refer to the same compound, which is worth knowing when searching for prior work because results are split across the names.
Can this be used in humans or animals?
No. This is supplied strictly as a laboratory reagent for in vitro research. It is not a medicine, it is not licensed for human or veterinary use, and it should not be administered to a person or an animal. We do not provide dosing or administration guidance.
Handy guides
- Reconstitution and solvents Choosing a solvent, adding it without damaging the peptide, working out concentrations, and the handling errors that cost people a vial.
- Storage and handling Temperature, light, reconstitution and shelf life, and what actually degrades a compound in practice.
- Freeze thaw cycles and shelf life What degrades a peptide in practice, how much a freeze thaw cycle actually costs you, and how to plan aliquots so it stops mattering.
- How to read a certificate of analysis A section by section walkthrough of a peptide certificate: what each figure means, what it does not mean, and the checks worth making before you accept a batch.
