Tirzepatide 30mg
Identity
- CAS number
- 2023788-19-2
- Molecular formula
- C225H348N48O68
- Molecular weight
- 4813.53
Physical form
- Appearance
- White lyophilised powder
- Purity
- 99%+ (HPLC)
- Solubility
- Soluble in bacteriostatic water
Handling
- Storage
- -20C, protected from light
- Shelf life
- 24 months from date of manufacture, sealed
Also known as LY3298176, GIP GLP-1 dual agonist
£118.00
Dual GIP and GLP-1 receptor agonist peptide, 30mg lyophilised. For receptor binding and signalling studies.
25 in stock
- Dispatch Same day if you order before the cut off, tracked
- Documentation Your batch certificate is emailed when it ships
- Storage -20C, protected from light
Please note: tirzepatide is a licensed prescription medicine in the UK. We supply it only as a laboratory reagent for in vitro research. If you need it for medical use, speak to your GP or a registered pharmacy.
Product description
A synthetic peptide with activity at both the GIP and GLP-1 receptors. Supplied lyophilised in a 30mg vial.
Research context
Tirzepatide is used in laboratory receptor binding and signalling studies, and its interest lies in the dual receptor activity rather than in any single pathway. Work with it typically compares selectivity and downstream signalling against single receptor agonists. It also appears in the literature under its development code LY3298176.
Handling notes
Reconstitute with bacteriostatic water. This is a large peptide and dissolution should be given time rather than accelerated with agitation or sonication. Store the sealed vial frozen and protected from light. Aliquot after reconstitution, since a 30mg vial represents a large amount of material to risk on repeated freeze thaw cycles.
Worth knowing
Frequently studied alongside retatrutide, which adds glucagon receptor activity to the same dual profile. If you are running a comparison, note that the two differ in molecular weight and plan working concentrations accordingly.
Documentation
This batch ships with its own certificate of analysis showing HPLC purity and mass spectrometry identity confirmation. The batch reference is recorded against your order, so a result generated months from now can be traced back to this specific lot.
Intended use
Supplied strictly for laboratory research use. Not a medicine. Not for human or veterinary consumption, and not for any diagnostic or therapeutic use.
Research background
The short version
Acts on two gut hormone receptors at once, GIP and GLP-1. This is the compound approved as a prescription medicine for diabetes and weight management, which makes the research use position here important to understand.
Tirzepatide is a synthetic peptide with agonist activity at both the GIP and GLP-1 receptors. It is the best clinically characterised compound in this catalogue by a wide margin, having gone through full phase three trials and regulatory approval as a prescription medicine.
Where it came from
Developed by Eli Lilly under the code LY3298176. Approved as a prescription medicine in multiple jurisdictions for type 2 diabetes and for weight management.
How it is thought to work
Dual agonism at GIP and GLP-1 receptors. The pharmacological interest is in whether the combination produces effects beyond what either receptor alone accounts for, and receptor level work continues to probe that.
Structural modification extends its half life considerably relative to native incretin hormones.
What it is studied for
What the published research found, and what it was tested in. We list the model against each one so you can judge how far the findings go.
- Receptor binding and selectivity Relative affinity and efficacy at GIP versus GLP-1 receptors. What they found Agonist activity confirmed at both GIP and GLP-1 receptors, with higher relative affinity at GIP than at GLP-1 in binding assays. Tested in Receptor binding assays, cell culture
- Downstream signalling Second messenger and beta arrestin recruitment profiles at each receptor. What they found Biased signalling reported at the GLP-1 receptor, favouring cAMP production over beta arrestin recruitment. Tested in Cell culture
- Comparative pharmacology Set against single receptor agonists and against triple agonists such as retatrutide. What they found Distinguished from single receptor agonists by the dual profile. Full phase three human data exists, since the compound is an approved medicine. Tested in Cell culture, rodent models
Specification
| CAS number | 2023788-19-2 |
|---|---|
| Molecular formula | C225H348N48O68 |
| Molecular weight | 4813.53 |
| Purity | 99%+ (HPLC) |
| Appearance | White lyophilised powder |
| Solubility | Soluble in bacteriostatic water |
| Storage | -20C, protected from light |
| Shelf life | 24 months from date of manufacture, sealed |
What you get
- The vial Tirzepatide 30mg. Sealed and labelled with the compound and its batch reference.
- Certificate of analysis For your batch specifically. Emailed when your order ships and available on this page now.
- Cold chain packaging Gel pack and insulation. We ship these early in the week so nothing sits in a depot over the weekend.
- Plain outer packaging Plain on the outside for your privacy. Everything inside is clearly labelled.
How it compares
How this compares to the compounds people usually weigh it against. Only the specs that actually differ are shown.
| Specification | This product Tirzepatide 30mg | Retatrutide 20mg | Retatrutide 40mg |
|---|---|---|---|
| Molecular weight | 4813.53 | 4731.30 | 4731.30 |
| Price | £118.00 | £145.00 | £268.00 |
Questions about this compound
How should Tirzepatide 30mg be stored?
Store the sealed vial at -20C, protected from light. Sealed and held at that condition it carries a shelf life of 24 months from date of manufacture, sealed from the date of manufacture. Once reconstituted, shelf life shortens considerably and the solution should be aliquoted before freezing rather than thawed repeatedly.
How is Tirzepatide 30mg reconstituted?
Soluble in bacteriostatic water. Add the solvent slowly down the inside wall of the vial rather than directly onto the material, then swirl gently to dissolve. Do not shake, vortex or sonicate to speed it up. A cloudy solution that will not clear usually means the wrong solvent rather than a poor batch.
What purity is this batch and how is it verified?
This item is supplied at 99%+ (HPLC), measured by high performance liquid chromatography. Identity is confirmed separately by mass spectrometry. Both results appear on the certificate of analysis for the batch you receive, not for a previous lot.
Can I see the certificate of analysis before ordering?
Yes. It is linked in the documentation section of this page. If no certificate is shown against this listing, ask before ordering rather than after.
Is Tirzepatide 30mg the same as the other names it appears under?
Yes. Tirzepatide 30mg also appears in the literature as LY3298176, GIP GLP-1 dual agonist. They refer to the same compound, which is worth knowing when searching for prior work because results are split across the names.
Can this be used in humans or animals?
No. This is supplied strictly as a laboratory reagent for in vitro research. It is not a medicine, it is not licensed for human or veterinary use, and it should not be administered to a person or an animal. We do not provide dosing or administration guidance.
Handy guides
- Reconstitution and solvents Choosing a solvent, adding it without damaging the peptide, working out concentrations, and the handling errors that cost people a vial.
- Storage and handling Temperature, light, reconstitution and shelf life, and what actually degrades a compound in practice.
- Freeze thaw cycles and shelf life What degrades a peptide in practice, how much a freeze thaw cycle actually costs you, and how to plan aliquots so it stops mattering.
- How to read a certificate of analysis A section by section walkthrough of a peptide certificate: what each figure means, what it does not mean, and the checks worth making before you accept a batch.
